In a two-page letter, federal well being officers and an unbiased panel of medical specialists accused AstraZeneca of cherry-picking data in regards to the effectiveness of its Covid-19 vaccine.

The corporate had stated that primarily based on its U.S. trial, the vaccine seemed to be 79 p.c efficient at stopping Covid-19. However the panel stated its efficacy might need been between 69 p.c and 74 p.c, and it reprimanded AstraZeneca for an excessively rosy description of the trial knowledge.

AstraZeneca defended the info it had launched on Monday and stated that the interim outcomes seemed to be “constant” with more moderen knowledge collected through the trial. The corporate stated it might reissue fuller outcomes inside 48 hours.

The outcomes throw a wrench into the efforts of elected leaders elsewhere to rebuild belief within the shot. Religion within the vaccine had already plunged throughout Europe after latest reviews {that a} very small variety of recipients had developed unusual blood clots.

Provide shortages: The European Union will immediately make public emergency laws permitting it to curb exports of Covid-19 vaccines manufactured within the bloc for the subsequent six weeks. The brand new guidelines will make it more durable for firms like AstraZeneca that produce Covid-19 vaccines within the E.U. to export them, and it’s more likely to disrupt provide to Britain.

Listed below are the latest updates and maps of the pandemic.


Two exit polls, along with early outcomes from Israel’s election, prompt no clear outcome on Tuesday night, leaving Prime Minister Benjamin Netanyahu and his potential right-wing allies with solely 60 seats, wanting the 61 wanted to kind a majority within the 120-seat Parliament.

A 3rd ballot gave an anti-Netanyahu bloc of events an fringe of 61 seats, probably blocking Mr. Netanyahu’s path to victory and making the election too near name. The uncertainty is more likely to result in weeks, if not months, of negotiations, and probably yet one more election.

Mr. Netanyahu campaigned on his document of dealing with the coronavirus pandemic, together with a vaccine rollout that’s the envy of the world. In search of re-election at the same time as he was on trial on corruption prices didn’t show deadly to his possibilities.

Potential authorities: Mr. Netanyahu’s wider bloc was anticipated by many to kind a coalition with Naftali Bennett, a rival right-winger, leaving Israel with probably the most conservative governments in its historical past, created from ultra-Orthodox events, ultranationalists, a bunch that campaigns in opposition to homosexual rights and one other whose chief backs expelling Arab residents of Israel deemed disloyal to the state.


Farmers from Punjab and elsewhere have camped exterior New Delhi in protest for 4 months. On the coronary heart of the dispute is a subsidy system that the federal government, economists and even many farmers agree is damaged.

The system was launched within the Nineteen Sixties to stave off a famine by encouraging farmers to develop wheat and rice. It included minimal costs set by the federal government, serving to farmers promote what they develop for a revenue.

However although the system is certainly outdated, Prime Minister Narendra Modi’s haste to remake it — his political occasion pushed new legal guidelines via Parliament in a matter of days — may devastate huge components of the nation the place farming stays a lifestyle. Our reporters looked at what went wrong and took stock of the protests now.

Context: Almost 60 p.c of India’s 1.3 billion individuals make a residing from agriculture, although the sector accounts for less than about 11 p.c of financial output. For a lot of, getting one other job isn’t an choice.

In 2017, a wierd interloper got here zooming via our photo voltaic system. Was it a comet? A cosmic iceberg? Or an alien house wreck?

Astronomers this month provided probably the most stable clarification but: Oumuamua, as it’s identified, was a chip off a faraway planet from one other photo voltaic system. Way back, a collision with an asteroid broke it off and despatched it careering via house.

TikTok’s affect is selling thousands of books. Some enthusiastic readers — largely girls of their teenagers and 20s — are posting movies of themselves studying or recommending novels. Often, they sob into the digicam after a very devastating ending.

“It turns into this very emotional 45-second video that folks instantly join with,” the director of books at Barnes & Noble advised The Occasions. “We haven’t seen all these loopy gross sales — I imply tens of hundreds of copies a month — with different social media codecs.”

One instance: “The Music of Achilles” by Madeline Miller. Gross sales spiked after a popular TikTok video final yr, and the guide is now promoting roughly 9 occasions as many copies per week because it was in 2012, when it gained a prestigious fiction award. The guide is presently third on the New York Occasions best-seller list for paperback fiction.

Seeing the potential, some publishers have begun paying — or sending free books to — customers with massive followings. The charges vary from a couple of hundred to a couple thousand {dollars} per publish. For now, although, the vast majority of these movies stay unsponsored, taking place organically.

Crunchy tofu coated in panko and sesame seeds pairs properly with a coconut-lime dressing in this vegetarian dish.

When you just like the farce and brotherly conflicts of “Frasier,” you would possibly just like the British comedy “Back,” which crams extra jokes and particulars right into a single episode than some exhibits handle in a season.

Lana Del Rey’s sixth major-label album, “Chemtrails Over the Nation Membership,” finds the singer “scaling again, looking for extra insular perception,” our critic writes.

Right here’s today’s Mini Crossword, and a clue: Used automobiles? (5 letters).

You can find all our puzzles here.


That’s it for immediately’s briefing. Have a beautiful Wednesday. — Natasha

P.S. The Occasions introduced its 2021-22 class of fellows, who come from throughout the U.S. in addition to Britain and Vietnam.

The most recent episode of “The Daily” includes a meals critic who misplaced her sense of odor from Covid-19.

Sanam Yar contributed reporting. You may attain Natasha and the group at briefing@nytimes.com.